LC-MS supported investigations on the metabolism of (+)-[F-18]flubatine, a radiotracer for imaging of alpha 4 beta 2 nicotinic acetylcholine receptors by PET

Ludwig Friedrich-Alexander; Fischer Steffen; Smits Rene; Deuther-Conrad Winnie; Hoepping Alexander; Patt Marianne; Sabri Osama; Brust Peter; Steinbach Joerg

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LC-MS supported investigations on the metabolism of (+)-[F-18]flubatine, a radiotracer for imaging of alpha 4 beta 2 nicotinic acetylcholine receptors by PET

机译：LC-MS支持对（+）-[F-18]氟丁定的代谢进行研究，氟丁汀是一种放射性示踪剂，可通过PET成像α4beta 2烟碱型乙酰胆碱受体

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《Journal of Labelled Compounds and Radiopharmaceuticals》 |2015年第suppla期|共1页
作者
Ludwig Friedrich-Alexander; Fischer Steffen; Smits Rene; Deuther-Conrad Winnie; Hoepping Alexander; Patt Marianne; Sabri Osama; Brust Peter; Steinbach Joerg;
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正文语种 eng
中图分类药学;
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1. LC-MS supported investigations on the metabolism of (+)-[F-18]flubatine, a radiotracer for imaging of alpha 4 beta 2 nicotinic acetylcholine receptors by PET [J] . Ludwig Friedrich-Alexander, Fischer Steffen, Smits Rene, Journal of Labelled Compounds and Radiopharmaceuticals . 2015,第Suppla期

机译：LC-MS支持对（+）-[F-18]氟丁定的代谢进行研究，氟丁汀是一种放射性示踪剂，可通过PET成像α4beta 2烟碱型乙酰胆碱受体
2. Imaging of cerebral alpha(4)beta(2)* nicotinic acetylcholine receptors with (-)-[F-18]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain [J] . Hillmer A. T., Esterlis I., Gallezot J. D., NeuroImage . 2016,第Null期

机译：脑α（4）β（2）β（2）*烟碱乙酰胆碱受体的成像（ - ） - [F-18]氟胺宠物：用血管致乙酰胆碱的实施推注加常数输注和敏感性
3. Imaging of cerebral alpha(4)beta(2)* nicotinic acetylcholine receptors with (-)-[F-18]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain [J] . Hillmer A. T., Esterlis I., Gallezot J. D., NeuroImage . 2016,第Null期

机译：（-）-[F-18]氟丁胺PET对脑α（4）β（2）*烟碱型乙酰胆碱受体的成像：推注加恒定输注以及对人脑中乙酰胆碱的敏感性
4. alpha-Conotoxin A10L PnIA analogues as probes for nicotinic acetylcholine receptors [C] . G.Hopping, D.A.Horton, R.J.Lewis, European Peptide Symposium . 2002

机译：α-conotoxin a10l pnia类似物作为烟碱乙酰胆碱受体的探针
5. Pharmacological properties of alpha4beta2 and alpha3beta4 nicotinic acetylcholine receptors: Ligand binding, activation, desensitization, and interspecies differences. [D] . Tuan, Edward Weikai. 2014

机译：alpha4beta2和alpha3beta4烟碱乙酰胆碱受体的药理特性：配体结合，激活，脱敏和种间差异。
6. LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-18FFlubatine—A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors [O] . Friedrich-Alexander Ludwig, René Smits, Steffen Fischer, 2016

机译：LC-MS支持氟巴汀对映体的体外代谢和（+）-18F氟丁的体内代谢研究-正电子发射断层显像放射配体对α4β2烟碱乙酰胆碱受体的成像
7. LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-(18)FFlubatine-A Positron Emission Tomography Radioligand for Imaging alpha4beta2 Nicotinic Acetylcholine Receptors [O] . Ludwig FA, Smits R, Fischer S, 2016

机译：LC-ms支持研究Flubatine的两种对映体的体外代谢和（+） - （18）F Flubatine-a正电子发射断层扫描放射性配体的α4β2烟碱乙酰胆碱受体的体内代谢。

LC-MS supported investigations on the metabolism of (+)-[F-18]flubatine, a radiotracer for imaging of alpha 4 beta 2 nicotinic acetylcholine receptors by PET

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