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Determination of Moxifloxacin used as Positive Controls for QT Prolongation in Human Plasma by LC-MS/MS

机译:LC-MS / MS用作人血浆中QT延长的阳性对照的测定

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A simple LC-MS/MS method has been developed and validated for the measurement of moxifloxacin in human plasma over the range of 25 - 5000 ng/mL. The incurred sample reproducibility assessment has been performed for a clinical study using the moxifloxacin assay. 99percent of the samples evaluated met the acceptance criteria.
机译:已经开发了一种简单的LC-MS / MS方法并验证用于测量人血浆中的Moxifloxacin,在25-5000ng / ml的范围内。使用Moxifloxacin测定法对临床研究进行了所产生的样品再现性评估。评估样本的99%达到了验收标准。

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