We report a microscale dual (signal and control) glucose sensor on a contact lens, and test its performance using a physiologically accurate eye model built on a polymer platform complete with fluidic channels mimicking tear ducts. We show that the sensor incorporated into a contact lens has enough sensitivity to detect glucose at levels found in the tear film. We also demonstrate that the differential design can be used to reject the impact of interfering chemicals found in the tear film such as ascorbic acid, lactate and urea. The test platform presented here enables the testing of contact lenses in a controlled environment that mimics the surface of the eye.
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