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Cell Nuclei Segmentation Combining Multiresolution Analysis, Clustering Methods and Colour Spaces

机译:组织核分割组合多分辨率分析,聚类方法和颜色空间

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In this paper a new method for medical images analysis has been proposed. It is based in a multiresolution schema in combination with a k-means clustering algorithm. The edge detection and classification schema is based on the analysis of the data obtained by a multiresolution image analysis (MRA) using Mallat and Zhong''s wavelet. The edge detection and classification algorithm developed has been tested defining five contour types: step, ramp, stair, pulse and "noise''. The cell nuclei presented in medical images can be perfectly isolated with the help of the "cellular nucleus'' contour, a special noise reduction achieved by means of the previous classification schema and a segmentation process provided by a k-means algorithm. We have proposed an algorithm to estimate the number of cells appearing in tissue samples, as well as the estimate of positivity levels in tumour tissues. This is part of a software tool for tumour detection and diagnosis of diseases.
机译:本文提出了一种新的医学图像分析方法。它基于与K-Means聚类算法组合的多分辨率模式。边缘检测和分类模式基于使用Mallat和Zhong'的小波通过多分辨率图像分析(MRA)获得的数据的分析。已经过开发的边缘检测和分类算法定义了五种轮廓类型:步骤,斜坡,楼梯,脉冲和“噪声”。在“蜂窝核心”轮廓的帮助下,可以完全隔离医学图像中的细胞核,通过先前的分类模式和由K-Means算法提供的分割过程实现了特殊的降噪。我们提出了一种算法来估计组织样品中出现的细胞数量,以及肿瘤组织中的阳性水平的估计。这是肿瘤检测和诊断疾病的软件工具的一部分。

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