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Cell Nuclei Segmentation Combining Multiresolution Analysis, Clustering Methods and Colour Spaces

机译:结合多分辨率分析,聚类方法和色彩空间的细胞核分割

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In this paper a new method for medical images analysis has been proposed. It is based in a multiresolution schema in combination with a k-means clustering algorithm. The edge detection and classification schema is based on the analysis of the data obtained by a multiresolution image analysis (MRA) using Mallat and Zhong''s wavelet. The edge detection and classification algorithm developed has been tested defining five contour types: step, ramp, stair, pulse and "noise''. The cell nuclei presented in medical images can be perfectly isolated with the help of the "cellular nucleus'' contour, a special noise reduction achieved by means of the previous classification schema and a segmentation process provided by a k-means algorithm. We have proposed an algorithm to estimate the number of cells appearing in tissue samples, as well as the estimate of positivity levels in tumour tissues. This is part of a software tool for tumour detection and diagnosis of diseases.
机译:本文提出了一种新的医学图像分析方法。它基于多分辨率方案,结合了k均值聚类算法。边缘检测和分类方案基于使用Mallat和Zhong的小波通过多分辨率图像分析(MRA)获得的数据分析。测试了开发的边缘检测和分类算法,定义了五种轮廓类型:阶跃,斜坡,阶梯,脉冲和“噪声”,可以借助“细胞核”轮廓完美地隔离医学图像中呈现的细胞核,通过先前的分类方案和k-means算法提供的分割过程实现的特殊降噪。我们提出了一种算法来估计组织样品中出现的细胞数量,以及对肿瘤组织中阳性水平的估计。这是用于肿瘤检测和疾病诊断的软件工具的一部分。

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