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Outcome of liver transplantation in adult population in Bulgaria

机译:保加利亚成年人口肝移植的结果

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Liver transplantation is treatment of choice for patients with end stage liver disease (ESLD). However, due to high surgical risk and risk of complications from the immunosuppressive agents pose significant challenges in transplanting setting. The aim of our study was to evaluate survival after liver transplantation. In this paper survival analysis is used to determine the prognostic significance of age of the recipient at the time of transplantation, sex, Model for End-Stage Liver Disease (MELD) score, complications after transplantation and treatment of complications, and to model the time it takes for death. The data is obtained from 41 patients, who have been transplanted at the University Hospital "Lozenetz", Sofia, Bulgaria in the period 2006-2019. For estimating event (death) free survival rate the Kaplan-Meier method is used. Time to event is calculated as the time from study entry to first event or date of last contact. Multivariate analysis is conducted by using Cox proportional hazards regression.
机译:肝移植是治疗的选择患者的终末期肝病(ESLD)。然而,由于手术风险大,并从免疫抑制剂并发症的风险造成移栽设置显著的挑战。我们研究的目的是评估肝移植术后存活。在本文中生存分析来确定的移植,性别,型号为终末期肝病(MELD)评分,移植和治疗并发症的术后并发症,并以时间模型的时间的接受者年龄的预后意义它需要死亡。该数据从41例患者,谁一直在2006至2019年期间在大学医院“的Lozenetz”,索非亚,保加利亚移植获得。用于估计事件(死亡)无瘤生存率使用Kaplan-Meier方法。时间对事件的计算公式为从研究开始到第一个事件或最后一次接触的日期和具体时间。多变量分析是通过使用Cox比例风险回归进行的。

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