RABIES IN LARGE ANIMALS; TRANSMISSION, DIAGNOSIS, PREVENTION AND OCCUPATIONAL SAFETY

摘要

Highly neurotropic, invariably fatal RNA virus of genus Lyssavirus; family Rhabdoviridae. At least 6 genotypes, with different major and minor antigenic variants, with resulting differences in host range and pathogenicity. "Fixed" strains have been serially propagated through laboratory animals with a resultant attenuation of virulence for other species, but increased pathogenicity in the species that they have been passaged. "Street" strains are obtained from natural infections from warm-blooded animals.