VETERINARY RTX TOXIN PRODUCING BACTERIA: PATHOGENESIS PREVENTION

摘要

Gram negative bacteria of veterinary significance that are known to encode RTX (repeats in the structural toxin) toxins include Actinobacillus equuli, Actinobacillus pleuropneumoniae (A. pleuropneumoniae), Actinobacillus porcifonsillarum, Actinobacillus suis, [Pasteurella] mairii and [Actinobacillus] rossii, Mannheimia haemolytica (M. haemolytica), Moraxella bovis (M. bovis), [Pasteurella] aerogenes and Bibersteinia (Pasteurella) trehalosi Recent studies also reported indirect evidence suggesting thepresence of RTX toxins in Avibacterium [Haemophilus] paragallinarum (Mena-Rojas et al., 2004) and Moraxella ovis (M. ovis). Recently we identified complete classical RTX operons in Moraxella bovoculi (M. bovoculi) isolated from infectious bovine keratoconjunctivitis (IBK; "pinkeye") affected dairy and beef calves in northern California, as well as in Moraxella ovis (M. ovis) originally isolated from sheep with conjunctivitis.