ASSOCIATIONS BETWEEN SWINE LEUKOCYTE ANTIGEN (SLA) CLASS I HAPLOTYPES AND TRAITS AFFECTED BY SALMONELLA INFECTION IN PIGS

摘要

The swine major histocompatibility complex antigens (SLA) present antigenic peptides to T-cells. Pathogens mutate antigenic proteins to evade this adaptive immune response, which puts pressure on the MHC to evolve extreme polymorphism. This protects both the individual and the population. The objective of the study was to determine if specific or homozygous SLA haplotypes were associated with increased susceptibility to Salmonellosis.