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Application of inkjet in tissue engineering and regenerative medicine: Development of inkjet 3D biofabrication technology

机译:喷墨在组织工程和再生医学中的应用:喷墨3D生物制作技术的发展

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Tissue engineering and regenerative medicine are hoped as the most promising advanced medicine of 21st century. Both are the most promising and reasonable approaches to save patients with organ failure, instead of transplantation. To date, simple and thin tissues have been successfully engineered such as skin and cartilage, however, a number of challenges are needed in engineering other thicker, larger and more complicated tissues and finally available organs. Biological tissues are composed of several types of cells and biomaterials, and have 3D architectures with micro-scaled resolution and macro-scaled mass. To engineer such tissues, printing technologies are promising, because the printer must print pictures on macro-scaled papers simultaneously with micro-scaled resolution. Then, we have developed 2D to 3D biofabrication using inkjet and hydrogel. 3D bioprinter has been developed using inkjet by our selves and several structures with hydrogel and living cells were fabricated. In this presentation, we introduce our progress of the research and development using inkjet technology. Digital fabrication including inkjet will provide promising and innovative approaches for sophisticated tissue engineering.
机译:组织工程和再生医学希望成为21世纪最有前景的先进药。两者都是拯救器官衰竭,而不是移植的最有前途和合理的方法。迄今为止,已经成功地设计了简单和薄的组织,例如皮肤和软骨,但是,在工程其他较厚,更大和更复杂的组织中,最终可用器官需要许多挑战。生物组织由几种类型的细胞和生物材料组成,并具有带有微缩放分辨率和宏观缩放质量的3D架构。为了工程师,印刷技术是有前途的,因为打印机必须在微缩放分辨率上同时在宏观缩放的论文上打印图片。然后,我们已经开发了使用喷墨和水凝胶的3D生物制作。 3D Biopreinter已使用喷墨通过我们的自身使用喷墨和水凝胶和活细胞的几种结构进行制造。在本演示文稿中,我们使用喷墨技术介绍了研究和开发的进步。数字制造包括喷墨将为复杂的组织工程提供有希望和创新的方法。

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