ANALYSIS AND CHARACTERIZATION OF GASTROINTESTINAL METABOLISM OF MAJOR SOY ALLERGENS GLYCININ AND ?-CONGLYCININ IN AN IN-VITRO MODEL BY LC-MS/MS

摘要

Soy is one of the eight major allergenic foods, that can cause severe reactions. But little is known so far about the fate of allergenic soy proteins during gastrointestinal digestion. Beside already published potential epitopic regions of different soy allergens with the ability to bind Immunoglobulin E and cause an allergic reaction, there is still no profound knowledge about kinetics of allergen degradation and characterization of degradation products [1].