Conformational equilibrium of single and double protonated 1,4-diamine-2-butenes by IRMPD spectroscopy

摘要

Polyamines like, spermidines, spermines, and their unsaturated counterparts, have important roles in cell growth and the putrescine metabolic route, acting as a modulator of normal and pathological cell growth. 1 Among these species, the diaminobutenes were shown to have enhanced efficiency as enzime inhibitors 2 and were proposed as a vector for cancer therapy and imaging 3.