Conformational preferences of protonated N-acetylated hexosamines probed by InfraRed Multiple Photon Dissociation (IRMPD) spectroscopy and ab initio calculations

摘要

Graphical abstractDisplay OmittedHighlights?First IRMPD study of protonatedN-acetyl hexosamines.?Disambiguation of HexNAc isomers, which could not be resolved by MS or MS/MS alone.?Resolution of competitive protonation sites.?Identification of the ring conformation and conformational heterogeneity.?Analysis of the contribution of individual anomers in heterogeneous IRMPD spectra.AbstractThe gas phase IR spectra of three protonatedN-acetyl hexosamines