Investigations on storage-induced changes of the red blood cell lipidome

摘要

Since more than forty years, athletes use blood doping techniques to improve the oxygen delivering capacity of the blood by artificially increasing the number of circulating red blood cells (RBCs). While the misuse of recombinant human erythropoietin can be directly detected in blood and urine specimens by using different analytical strategies only indirect approaches such as the monitoring of blood parameters within the athlete biological passport or the detection of phthalates are currently available to provide sufficient evidence for autologous blood transfusions (ABT).