Abberant Glyosylation in Skin Tissue of Atopic Syndrome Patients

摘要

Up to now human skin glycome profiling by nano-LC/MS has not yet reported. In this study, Based on qualitative and quantitative human skin glycome profiling, human skin samples (stratum corneum) from atopic syndrome patients (n=30) and healthy control individuals (n=30) revealed altered glycosylation trends. These findings may lead to the discovery of biomarkers for atopic syndrome and further functional analysis will provide a better understanding of the biological mechanisms of human skin tissue.