High resolution mass spectrometry based metabolomics: a new tool to detect and characterize emerging pollutants in water and food matrices.

摘要

Food trade globalization and extensive use of pesticides and drugs in agriculture and farming has increased the risk of food contamination and fraud. This has become a significant public health problem resulting in strengthened controls from the health authorities. However, the analytical methods used to detect pollutants are limited to targeted approaches towards expected contaminants, which prevent the possibility of finding unexpected or emerging contaminants. High resolution mass spectrometry (HRMS) based metabolomics associated with data mining can address this issue through monitoring of targeted compounds, but also to highlight and identify unexpected compounds. Part of the research described was carried out under the AgriFood GPS project funded by Bpifrance (http://agrifoodgps.sharepoint.com).