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Quantitation of MET using Mass Spectrometry for Clinical Application: Correlation with IHC and MET Gene Amplification in FFPE Tumor Tissue

机译：用质谱法定量临床应用：与IHC的相关性，并在FFPE肿瘤组织中得到基因扩增

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The OncoPlexDx multiplexed assay measures the absolute level of MET and the other targets in clinical tumor FFPE tissue with high precision. Compared to IHC, SRM provided a quantitative and linear measurement of MET expression, reliably distinguishing between non-amplified and amplified MET tumors at a cut-off point of >1500 amol/ug.

机译：oncoplexdx多路复用测定测量临床肿瘤FFPE组织的绝对水平和高精度。与IHC相比，SRM提供了MET表达的定量和线性测量，可靠地区分在> 1500AMOL / UG的截止点处的非扩增和扩增的态肿瘤。

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《International Mass Spectrometry Conference》|2014年||共2页
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Todd Hembrough; Wei-Li Liao; Sheeno Thyparambil; Les Henderson; Brittany Rambo; Fabiola Cecchi; Donald Bottaro; Kathleen Bengali; Marlene Darfler; Peng Xu; Shu-Yuan Xiao; Jon Burrows; Daniel Catenacci;
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中图分类分析化学;
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1. Absolute quantitation of MET using mass spectrometry for clinical application: assay precision, stability, and correlation with MET gene amplification in FFPE tumor tissue [J] . Cecchi F., Liao W. L., Thyparambil S., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2014,第Suppla6期

机译：使用质谱对MET进行的临床应用的绝对定量：FFPE肿瘤组织中测定的准确性，稳定性以及与MET基因扩增的相关性
2. Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH [J] . Catenacci Daniel V. T., Liao Wei-Li, Zhao Lei, Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association . 2016,第4期

机译：基于质谱的胃食管肿瘤组织中Her2的定量：与IHC和FISH的比较
3. A technique for relative quantitation of cancer biomarkers in formalin-fixed, paraffin-embedded (FFPE) tissue using stable-isotope-label based mass spectrometry imaging (SILMSI) [J] . Wang Hong, DeGnore Jon P., Kelly Brian D., Journal of mass spectrometry: JMS . 2015,第9期

机译：使用基于稳定同位素标记的质谱成像（SILMSI）对福尔马林固定的石蜡包埋（FFPE）组织中的癌症生物标记物进行相对定量的技术
4. Quantitation of MET using Mass Spectrometry for Clinical Application: Correlation with IHC and MET Gene Amplification in FFPE Tumor Tissue [C] . Todd Hembrough, Wei-Li Liao, Sheeno Thyparambil, International Mass Spectrometry Conference . 2014

机译：用质谱法定量临床应用：与IHC的相关性，并在FFPE肿瘤组织中得到基因扩增
5. Combining laser capture microdissection and MALDI mass spectrometry for tissue protein profiling: Methodology development and clinical applications. [D] . Xu, Baogang Jonathan. 2005

机译：结合激光捕获显微切割技术和MALDI质谱技术进行组织蛋白分析：方法学的发展和临床应用。
6. Absolute Quantitation of Met Using Mass Spectrometry for Clinical Application: Assay Precision Stability and Correlation with MET Gene Amplification in FFPE Tumor Tissue [O] . Daniel V. T. Catenacci, Wei-Li Liao, Sheeno Thyparambil, -1

机译：使用质谱法对大都会进行的绝对定量：临床应用：FFPE肿瘤组织中的测定精度稳定性以及与MET基因扩增的相关性
7. Absolute quantitation of Met using mass spectrometry for clinical application: assay precision, stability, and correlation with MET gene amplification in FFPE tumor tissue. [O] . Daniel V T Catenacci, Wei-Li Liao, Sheeno Thyparambil, 2014

机译：使用质谱法对met进行绝对定量以用于临床应用：测定精确度，稳定性以及与FFpE肿瘤组织中的mET基因扩增的相关性。

Quantitation of MET using Mass Spectrometry for Clinical Application: Correlation with IHC and MET Gene Amplification in FFPE Tumor Tissue

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