Lewisite and VX Degradation By-Product Method Development for Environmental Remediation by Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

摘要

A novel LC-MS method was developed for CVAA and CVAOA in environmental matrices. The presence of CVAOA and/or CVAA is indicative of Lewisite 1 contamination, as there are no known natural sources for these compounds. The method was successfully tested with real-world samples suspected of containing Lewisite. In addition to the target analytes, the LC-MS method analyzed for thirteen additional As by-products, not possible by GC-MS or ICP-MS analysis techniques, and correctly identified the arsenic contamination.