Fluorene derivatives as MALDI matrices for Electron Transfer ionization

摘要

FLs (CN, CH_3, OCH_3) promote effective electron transfer ionization reactions, under MALDI conditions, for model analytes (porphyrins and pthalocyanins). FLs provide mixture coverages of 100% and exceptional analytical performance, in terms of S/N, M:A molar ratios and vacuum stability when compared with a commercially available ET-matrix (DCTB). For real sample analysis (petroporphyrin fraction from a heavy crude-oil) the FL-OCH_3 derivative allows mixture coverage above 80%, in comparison with the 48% observed with DCTB.