Use of halogenated cyanocinnamic acid derivatives as matrices in MALDI mass spectrometry

摘要

The present invention relates to the use of a halogenated cyanocinnamic acid derivative of the general formula: where R is independently selected from among F, Cl, and Br, n = 3, 4, or 5, R' is selected from among COOH, CONH₂, SO₃H, and COOR", and R" = C₁-C₅ alkyl; and/or of 4-brom-α-cyanocinnamic acid and/or of α-cyano-2,4-dichlorocinnamic acid in a matrix for MALDI mass spectrometry of an analyte.