Investigation of Pseudomonas aeruginosa lipopolysaccharide transporter subunit LptA oligomerization by chemical crosslinking and nanoLC-tandem mass spectrometry

摘要

Crosslinking showed that the dimer was the dominant species for P. aeruginosa LptA, with much smaller amounts of trimer and tetramer. SEC-MALS showed only dimers present at all concentrations (up to 60 mM) for non-crosslinked P. aeruginosa LptA.