Automated Detection of Trace Level Basic and Acidic Pesticides and Herbicides in Drinking Water by Online SPE LC/MS

摘要

The analysis of pesticides and herbicides in drinking water by online SPE LC/6460 triple quadrupole MS delivers a method applicable for an available kit containing compounds of both acidic and basic classes. Their performance is demonstrated. All compound delivered excellent linearity, LLOQs and LODs at low level. Peak area RSDs and retention time RSDs as well as recoveries were excellent for the applied online SPE method. Automatic online SPE is superior to tedious offline SPE with much less solvent consumption and labor cost for water quality analysis. All components are controlled under one software package and this makes method development much easier to conduct.