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Manipulation of superparamagnetic beads using on-chip current lines placed on a ferrite magnet

机译:使用在铁氧体磁体上的片上电流线进行超顺磁珠的操纵

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Manipulation of superparamagnetic beads in a static solution is demonstrated using on-chip current striplines placed on a ferrite magnet. The ferrite magnet fits the requirement to enhance the bead's magnetic moment while still keeping beads randomly dispersed in the liquid, so allowing easy and selective manipulation of single beads. By applying currents up to hundreds of milliampere, the tapered stripline first attracts the beads to its edge, then the magnetic force along the edge drives the trapped beads moving continuously towards the chip center. On arriving into the chip central area (a square zone which acts as a site to collect the arriving beads), fine manipulation of selected single beads is further performed by switching on/off and/or tuning the current passing through the nearby quadruple striplines. We suggest that the present system may provide a simple but effective platform for handling magnetic tags for biological and biomedical applications.
机译:使用在铁氧体磁体上的片上电流带线证明了静态溶液中超顺磁珠的操纵。铁氧体磁铁符合要求增强珠子磁矩,同时保持珠子随机分散在液体中的珠子,因此允许简单且选择性地操纵单珠。通过施加高达数百毫安的电流,锥形带状线首先将珠子吸引到其边缘,然后沿边缘的磁力驱动捕获的珠子,捕获的珠子连续地向芯片中心移动。在到达芯片中央区域(用作设定的方形区域以收集到达珠子),通过接通/断开和/或调谐通过附近的四重带状线的电流进一步进行精细操纵所选择的单珠。我们建议本系统可以为处理生物和生物医学应用的磁标签提供简单但有效的平台。

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