Chemopreventive effect of aminosalicylates

摘要

Colorectal cancer represents a serious risk for patients suffering from left-sided colitis or pancolitis ~3. Risk factors include primary sclerosing cholangitis, young age of onset, and a family history of colorectal cancer. Probable risk factors are a high intestinal inflammatory activity, backwash ileitis and folate deficiency. Several clinical strategies aim at the prevention of colorectal cancer in ulcerative colitis: (UC):Surveillance colonoscopy is recommended 8 years and 15 years after the onset of the disease in patients with pancolitis and left-sided colitis,respectively.