How to diagnose Behcet's and intestinal Behcet's disease?

摘要

Behcet's disease (BD) was first described by Hulusi Behcet, as a triad consisting of aphthous stomatitis, genital ulcers and uveitis1. It was later shown that many organs, including joints and other systems, e.g. pulmonary and neurological systems, can be affected.Although generally considered as a vasculitis there can be lesions, e.g. in the central nervous system, in which a clear-cut vascular disease cannot be discerned. There is no distinctive histological characteristic.The underlying cause is unknown, but it seems to be a multifactorial disease in which genetic components and external factors jointly influence the course and clinical expression of disease. Histologically, CD4~+ T lymphocytes seem to be major cell type in inflammatory infiltrates5 and peripheral T cells have a predominant Thl-type cytokine pattern, suggesting a role of T cell-mediated immune response in the pathogenesis.