Autoimmune chronic hepatitis combined with coeliac disease and IgA deficiency

摘要

A 5-year-old boy (father Irish, mother Hispanic) presented with a history of chronic diarrhoea and vomiting, Hirschsprung-like abdomen, wasted weak muscles, abdominal pain and anorexia. Gluten antibodies (AGA, EMA) were reported as negative, aminotransferases elevated, albumin very low. The first diagnosis was coeliac disease and secondary hepatotoxic injury, complicated by IgA-deficiency.