Extended pancreaticoduodenectomy with or without vessels resection for periampullary adenocarcinoma

摘要

This retrospective, single-institution trial was designed to evaluate the end points of mortality, morbidity, and survival in patients undergoing extended pancreaticoduodenectomy without vessels resection versus the same procedure with vascular reconstruction for periampullary adenocarcinoma (including superior mesenteric vein, portal vein and hepatic artery). Between January 2003 through July 2008, 106 inpatients with periampullary cancer received pancreaticoduodenectomy, 26 of them underwent superior mesenteric vein and/or portal vein reconstruction, where prosthesis replacement was used in 5 instances. The reconstructions of the superior mesenteric artery and/or hepatic artery were performed in 2 patients. In conclusion, the extended pancreaticoduodenectomy with vessels reconstruction can be sufficient alternative in the aspect of postoperative morbidity and nutritional support. However, the improvements of adjuvant systemic strategies with pancreatic adenocarcinoma are necessary.