Poly(propylene Fumarate) : Molecular Weight Dependence Of Physical Properties

摘要

Recently developed injectable materials have fulfilled many design criteria for diverse orthopedic applications. One promising candidate material of this type is poly(propylene fumarate) (PPF) (Scheme 1) that can be crosslinked through its fumarate double bonds.~1 Although many efforts have been made to explore the applications of PPF-based materials, there still lacks comprehensive physical characterizations and rheological understanding of such material. Here we report the molecular weight dependences of several important parameters such as glass transition temperature (T_g), thermal degradation temperature (T_d), polymer density p, and rheological properties. Such characterization allows better understanding of the PPF materials and its use in orthopedic tissue engineering applications.