Microfluidic device for immobilization of bio-vesicles towards controlled on-chip electrofusion

摘要

We describe a microfluidic device that combines microfluidic and electrical manipulation of cells or artificial vesicles in order to perform well controlled electrofusion. Primary vesicles are immobilized by suction onto a silicon array of microholes. Secondary vesicles are aligned on the first ones using dielectrophoresis.