Biodegradable Disulfide-based Linear Polyethylenimine for Gene Delivery Carrier

机译：基于生物降解的二硫键基因递送载体的线性聚乙烯亚胺

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Polyethylenimine shows the highest transfection efficiency among nonviral gene delivery carriers but it has very high cytotoxicity. To reduce the cytotoxicity as well as to maintain the efficiency, we synthesized the disulfide-based linear PEI and tested it for gene delivery.

机译：聚乙烯亚胺显示出非血管基因递送载体中的最高转染效率，但具有非常高的细胞毒性。为了减少细胞毒性以及保持效率，我们合成了基于二硫化二硫化的线性PEI并测试了基因递送。

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《Controlled Release Society annual meeting》|2004年||共1页
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中图分类生物工程学（生物技术）;
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1. Synthesis of biodegradable polycationic methoxy poly(ethylene glycol )-polyethylenimine-chitosan and its potential as gene carrier [J] . Zhigang Xu, Xiaoping Wan, Wei Zhang Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2009,第1期

机译：可生物降解的聚阳离子甲氧基聚乙二醇-聚乙烯亚胺-壳聚糖的合成及其作为基因载体的潜力
2. Biodegradable poly(ester amine) based on glycerol dimethacrylate and polyethylenimine as a gene carrier [J] . Arote RB, Hwang SK, Yoo MK, The journal of gene medicine . 2008,第11期

机译：基于二甲基丙烯酸甘油酯和聚乙烯亚胺作为基因载体的可生物降解的聚（酯胺）
3. A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier [J] . Arote R, Kim TH, Kim YK, Biomaterials . 2007,第26期

机译：基于聚己内酯和聚乙烯亚胺作为基因载体的可生物降解的聚（酯胺）
4. Biodegradable Disulfide-based Linear Polyethylenimine for Gene Delivery Carrier [C] . Controlled Release Society annual meeting . 2004

机译：基于生物降解的二硫键基因递送载体的线性聚乙烯亚胺
5. Development of Low Cytotoxic and HIgh Efficient Disulfide-based Polyethylenimine Non-viral Vectors for In-vitro Gene Transfection [D] . Deng, Rui 2010

机译：低细胞毒性和高效率的基于二硫键的聚乙烯亚胺非病毒载体的体外基因转染的开发。
6. Synthesis and properties of a novel biodegradable poly(ester amine) copolymer based on poly(L-lactide) and low molecular weight polyethylenimine for gene delivery [O] . Qing Fa Guo, Ting Ting Liu, Xi Yan, 2011

机译：基于聚L-丙交酯和低分子量聚乙烯亚胺的新型可生物降解聚（酯胺）共聚物的合成及性能
7. Synthesis and properties of a novel biodegradable poly(ester amine) copolymer based on poly(L-lactide) and low molecular weight polyethylenimine for gene delivery [O] . Guo, Qing Fa, Liu, Ting Ting, Yan, Xi, 2011

机译：基于聚L-丙交酯和低分子量聚乙烯亚胺的新型可生物降解聚（酯胺）共聚物的合成及性能

Biodegradable Disulfide-based Linear Polyethylenimine for Gene Delivery Carrier

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