High-resolution analysis of Y-biallelic markers in three populations from Sao Tome e Principe

摘要

Twenty Y-chtomosome biallelic polymorphisms were analysed in samples from Angolares, Forros and Tongas, three population groups from the African archipelago of Sao Tome e Principe Although most male lineages belonged to Sub-Saharan haplogroups, the component of European origin reached 23.9% in the archipelago as a whole. This value contrasts with the previously reported absence of European female lineages in the Sao Tomean mtDNA pool and reflects the strong sex-biased admixture process between Europeans and Africans that characterized the demographic history of the archipelago. The lowest diversity levels as well as the smallest proportion of putative male European ancestry were registered among the Angolares, representing clear genetic signs of their past relative isolation from other Sao Tome e Principe's inhabitants.