A novel and effective procedure for removing HIV4 RNA from human semen

摘要

The objectives of this study were to determine the effectiveness of a novel treatment designed to remove HIV from semen by combining multiple density gradients and a pioteolytic enzyme and to evaluate speim viability after treatment. The procedure was effective for reducing viral copies in spiked semen to clinically insignificant levels. The procedure had a statistical vs clinical significance on reducing the motility (but not supr avital staining) of cryopreseived sperm at 0 and 2 h; however, no differences were observed after 24 h.