D-dimer Levels in Long Term Anticoagulated Patients

摘要

The natural history of positive D-dimers during chronically orally anticoagulated patients it is not well defined. In this study, we prospectively measured D-dimer levels in 28 patients at least three times.32% of them had at least one positive result. We noticed a great degree of D-dimer levels' fluctuation. Unfortunately no CRP values were available. Only one patient (3,5%) had persistently positive D-dimer results, obviously due to the coexisting cirrhosis. In our study elevated D-dimer levels do not appear to identify a higher risk group for thrombosis. These preliminary data suggest that D-dimer levels obtained during anticoagulation should be translated carefully due to the high number of false-positive results, especially in those patients with cormobid condition.