Development of a New Calcium Phosphate Glass Ceramic Porous Scaffold for Guided Bone Regeneration

摘要

In this work, different porous scaffolds were developed using calcium phosphate glass particles in the system Os-CaO-NaiO-TiCh) and H2O2 as foaming agent. The different 3D structures were obtained by varying the foaming agent content and the thermal treatment. The microstructure and morphology of the specimens were observed by SEM (Scanning Electron Microscopy) and the percentage of porosity was quantified by image analysis. XRD (X Ray Diffraction) was used to study the formation of new crystalline phases. The results showed that a increase in the amount of H2O2 solution mixed with the glass particles increased both, the number ' of pores and their size. Indeed, the percentage of porosity ranged between 35% and 55% and the pore size varied from 100 to 500jxm for the samples with 40 and 60% w/w of H2O2 respectively. The thermal treatments induced the formation of crystalline phases in the material. After sintering at 540deg CC a vitreous phase was the predominant, while at 570deg CC, the percentage ofcrystalline phases was higher The crystalline phases detected were meta and pyrophosphates. The pores sizes and interconnectivity obtained were in good agreement with those demanded for bone engineering scaffolds.