Effect of static magnetic field on osteoporotic bone

摘要

The effects of a static magnetic field on bone formation was investigated using rats. Mild osteoporotic models were created by surgical methods, including ligating the femoral arteries of rats. Tapered rods made of magnetized samariun cobalt were implanted into the middle diaphysis of 110 rat femurs. The femoral arteries of these rats were ligated to create an ischemic bone model. The result revealed that the femurs adjacent to the magnetized specimens had significantly higher bone mineral density (BMD) than those adjacent to the unmagnetized specimens at 12 weeks after implantation. The result at the 3rd week post-implantation revealed that the BMD of the ischemic bone model rats was significantly reduced, compared with that of non-operated femur, bul the magnetized group had significantly higher bone weights than the unmagnetized (P = 0.0117). The BMD of the rats implanted with the magnetized rods was similar to that of the non-operated rats. The enhancement of the femural bone formation of the ischemic rat model by the static magnetic field seems to be due to the improved blood circulation of the femur.