Bismuth-Catalyzed Intramolecular Addition of Carboxylic Acids to Alkynes

摘要

The importance of metal-catalyzed heterofunctionalization of carbon-carbon multiple bonds has been widely recognized in organic synthesis and much effort has been made towards exploiting this methodology.Using this transformation was drastically developed by a high alkynophilicity of the noble metal catalysts such as gold,silver,platinum,and mercury species.Despite excellent results in the field,these complexes were expensive or toxic materials,and not suitable for industrial use.Therefore,the development of the more practical catalytic system is desired.