Role of the branched-chain amino acid aminotransferases on the production of volatile compounds by Saccharomyces cerevisiae

摘要

In yeast, two distinct branched chain amino acid (BCAA) aminotransferases are responsible of both amino acid biosynthesis and catabolism; the BAT1 is mitochondrial and the BAT2 is cytosolic. The deletion of BAT2 in an haploid yeast strain leads to an important decrease in isobutanol and isoamylalcohols concentrations during growth on YPD medium. On minimal medium, the BAT2 deletion does not have any influence on the higher alcohol production. Moreover, an significant increase in higher alcohol production is observed with the mutant strain bearing the BAT1 deletion in both growth medium.