Development of bioactive polysulfone nanocomposites for bone tissue replacement

摘要

In view of the growing number of traffic accidents and human life expectancy, bone is emerged as the most frequently transplanted human tissue and its demand is growing in medical market for reconstruction of bone defects. So researchers in the field of orthopedics have given considerable emphasis on the fabrication of reliable and economically feasible biomaterials for bone tissue replacement and regeneration applications. Current methods of broken and defective bone treatment use metal orthopedic implants, unfortunately shows many shortcomings such as insufficient prolonged bonding between the implanted material and juxtaposed bone, different mechanical properties between bone and the implant leading to stress shielding, release of certain ions and corrosion products from metallic implants and the need of second surgery to remove the implant.