BIOCOMPATIBLE COMPOSITION FOR REPLACEMENT (TREATMENT) OF PARTIAL AND TOTAL DEFECTS OF CARTILAGINOUS AND BONE TISSUE AND METHOD FOR PREPARING BIOCOMPATIBLE COMPOSITION FOR REPLACEMENT (TREATMENT) OF PARTIAL AND TOTAL DEFECTS OF CARTILAGINOUS AND BONE TISSUE

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine and concerns a preparations applied for prevention and treatment of disturbed physiological and reparative regeneration of bone tissue and articular cartilage. The composition includes synthetic hydroxyapatite, chitosan gel with bactericidal properties, being a matrix to contain an aqueous solution of preparation "Adgelon", containing serum glycoprotein of the cattle blood. The composition is prepared by mixing hydroxyapatite, chitosan gel with preparation "Adgelon" immobilised on chitosan gel.;EFFECT: composition provides improved stimulant property for reparative osteogenesis with restoration of morphologically normal bone matrix.;2 cl, 3 ex