CAPTURE-AND-RELEASE CONCENTRATION OF BACTERIA USING FREE-FLOW ZONE ELECTROPHORESIS

摘要

A microfluidic free-flow zone electrophoresis device was developed for the purpose of concentrating biological particles in buffer. This device utilizes the novel technology of "capture-and-release," a semi-continuous process that improves upon previous filtration procedures. Low and high throughput designs of this device were tested with solutions of bacteria in various buffers. Concentration factors as high as 4.5 were achieved.