Incidence of Ventricular Septal Rupture Complicating Acute Myocardial Infarction in Multi-Ethnic Asian Population after Acute Coronary Intervention: Single Centre Experience

摘要

Incidence of Ventricular Septal Rupture (VSR) complicating acute ST elevation myocardial infarction (STEMI) has been significantly reduced from 2% prior to re-perfusion era to 0.2% with reperfusion strategy. There are limited data available on incidence of VSR in the era of primary percutaneous coronary intervention (PCI) in acute STEMI patients in multi-ethnic Asian cohort. In this paper, a total of 275 patients with acute STEMI underwent primary PCI from January 2008 till December 2008. 3 patients (1.1%) developed VSR. The median time from symptom onset to VSR diagnosed by transthoracic echocardiography was 9 hours. 2 patients underwent VSR repair but none of the 3 patients survived the index hospitalization. Incidences of VSR in our centre is 1.1%, which is higher compared with previous published reports. Prognosis remains poor for these patients despite early primary PCI.