Inflammatory Markers and Cardiac Troponin-I in Acute Myocardial Infarction

摘要

Vascular inflammation plays a pivotal role in atherosclerotic plaque stability and a variety of inflammatory markers are known to be involved1. These markers include cell adhesion molecules, inflammatory cytokines and pro-atherogenic enzymes. Many of these markers have yet to prove their clinical usefulnessIn the acute coronary syndromes, C-Reactive Protein (CRP) has short and long term prognostic capability, independent of, but additive to, that of the cardiac troponins. Our objective was to study the relationship between inflammatory-cytokine precursors of CRP, as well as an atherosclerotic plaque proteinase to cardiac Troponin I (cTnI), the diagnostic marker for myocardial lesion, in acute myocardial infarction (AMI).