Surgical Outcome of Superficial or Deep Castleman Disease

摘要

Background: Castleman disease is a rare lymphoproliferative disease of low malignant potential, Surgery, chemotherapy, immunotherapy, and radiation therapy have all been used to manage the disease. We retrospectively reviewed 20 cases of Castleman disease to evaluate if the site of the lesions, i.e., superficial or deep, influences the surgical outcome. Methods: 20 patients operated on for Castleman disease from 1994 to 2003 were included. We compared the recurrence and mortality rate in patients between the 2 groups. Results: Among 19 patients who had complete resection (18 with unicentric and 1 with multicentric disease), there has been no evidence of recurrence. Conclusion: Whether Castleman disease is superficial or deep has no impact on surgical outcome as long as resection is complete,