THE EFFECTS OF LOW LEVEL PROLONGED MICROWAVE IRRADIATION ON TUMOR-BEARING MICE

摘要

The effects of low density centimetric waves (8.15-18 GHz, 1 μW/cm~(2), 1.5 h daily for 14 days; MW) on tumor necrosis factor (TNF) production in macrophages of mice with different growth rate of cancer solid tumors produced by hypodermic injection in hind legs of Ehrlich carcinoma ascite cells were studied. After irradiation, stimulation of TNF production in immunocompetent cells of healthy and, especially, of tumor-bearing animal was detected; and this effect was higher upon exposure of mice carrying tumors of fast growth rate. We suggest that the significant immunomodulating effect of low density microwaves can be utilized for tumor growth suppression.