Prediction of binary interaction coefficient and critical parameters of cholesterol in supercritical carbon dioxide

摘要

In this work, the cholesterol concentration in the supercritical (SC) CO2, under working conditions, is calculated by implementing the modified Peng Robinson equation of state (EoS) combined with the Van Der Waals mixing rules. Here, optimisations of the interaction coefficient (k_(ij)) between solvent and solute and the solute critical parameters (i.e. critical pressure and temperature) are the main issue to get precise calculations of the dissolved mole fraction in SC CO_2.