Molecular-electronic mechanism of the toxicity of dioxin and ability of some natural structures to concurrently interact to inhibit its activity

摘要

Numerous particular ESR line groups from Dioxin (2,3,7,8-TCDD) in biological fat and oil, and from its interaction effects in human blood and liver have been revealed and interpreted on the basis of the exchange combinations of the π-electrons of the Dioxin molecule and their specific super-exchange complexes with the structures of the nuclei of the respective proteins. On the other hand, the results achieved in long-term experimental clinical studies suggest that some special biological natural compounds from traditional sources are able to inhibit the toxicity of Dioxin. On the basis of the ESR and also the HPLC experimental results, we have revealed some new active natural complexes present in special vegetable products. These complexes are able to bind strongly to Dioxin molecules, thereby inhibiting the toxicity of Dioxin, and its carcinogenic activity.