Stilboflavins,a natural peptaibol library from the mold stilbella flavipes

摘要

We have recently reported on the isolation of a mixture of polypeptides of the peptaibol group from the mold Stilbella flavipes,strain CBS 146.81.Groups of peptides isolated by preparative TLC were named stilboflavins (SF),A,B,and C.The sequnces of SF B were investigated by ESI-MS,GC-MS and quantitative amino acid analysis and shown to represent a mixture of 10 microheterogeneous N-acetylated 20-residue peptides distinguished by exchange of certain amino acids,as well as C-terminal amino alcohols,valinol,leucinol and isoleucinol.We now report on the sequences of SF A peptides and their relation to SF B peptides.For full details we refer to the literature.