Stabilization of the triple helix of collagen peptides using fluoroproline and/or triacid scaffolds

摘要

The collagen triple helix is composed of three separate peptide chains,which are stagered by one residue and intertwine to form a right-handed triplex helix.The primary structure of these peptides is characterized by trimeric repeating units X-Y-G,where X and Y can be any amino acid.