Diagnostic laboratories commonly use the disc sensitivity method to determine the antibiotic susceptibility of bacteria. Inaccuracies are inherent in this test method. The Etest (AB Biodisc, Solna, Sweden) is a method which is easy to use and assesses the minimum inhibitory concentration (mic) of the antibiotic. Many previous studies have shown that the results of the Etest correlate well with other methods of determining the mic. This study was undertaken to see if there is any correlation betweenthe mic determined by Etest and the measured zone of inhibition of the disc method using trimethorprim potentiated sulphonamide. Actinobacillus pleuropneumoniae (n=43), Pasteurella multocida (n=17), Alt. suis (n=3), A. pyogenes (n=1) and S suis (n=4) were isolated from between 1995 and 1997 inclusive from pigs' lungs in the UK. The pigs had clinical disease and originated from different farms. Their previous treatment was not known.
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