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Combined Optical and Ultrasound-Based Tracking of an Acoustic Radiation Force-Induced Excitation

机译:基于光学和超声波的声学跟踪声辐射力引起的激励

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Acoustic radiation force (ARF) has become a common excitation mechanism in elasticity imaging; however, the high acoustic intensities and subsequent generation of harmonics hamper the effectiveness of using conventional radio frequency (RF) tracking to investigate the dynamics of tissues and catheter-based transducers, especially during the excitation. Thus, in trying to gain a better understanding of their response to ARF excitations, a more robust tracking option could prove useful. We propose a combined optical-ultrasound tracking method, where the dynamic response resulting from an ARF-induced excitation in soft tissue and on an unbounded catheter is tracked during and after insonification. Both impulsive and harmonic (i.e. amplitude-modulated) excitations were investigated. The displacement estimates obtained from the optical method were then compared to those obtained from the more conventional ultrasound-based method. For the impulsive excitation case (pulse length ≥1.3 ms), the mean absolute percent difference between the peak displacements estimated by the two methods was 4.0%. For the harmonic excitation case, the mean absolute percent difference between amplitude estimations obtained from the two techniques was 7.4% at lower frequencies (50-200 Hz) and 29.1% at 500 Hz. The relatively large disparity between the displacement estimates at higher frequencies is thought to be a result of the finite length of the tracking marker, which was assumed to move as an infinitesimal point. Given the good agreement seen for the harmonic case at lower frequencies and the impulsive case at longer pulse lengths, this technique could be insightful in future investigations of tissue/transducer response to ARF-induced excitations in controlled, experimental settings.
机译:声学辐射力(ARF)已成为弹性成像中的常见激发机制;然而,高声学强度和随后产生的谐波妨碍了使用传统射频(RF)跟踪的有效性来研究组织和基于导管的换能器的动态,尤其是在激发过程中。因此,在尝试更好地了解他们对ARF激励的响应时,更强大的跟踪选项可能是有用的。我们提出了一种组合的光学超声跟踪方法,其中在胰术期间和之后跟踪由软组织和未绑定导管中的ARF引起的激发产生的动态响应。研究了脉冲和谐波(即幅度调节的)激发。然后将从光学方法获得的位移估计与从更常规的超声波基方法获得的那些进行比较。对于冲动激励案例(脉冲长度≥1.3ms),两种方法估计的峰位差异的平均绝对差异为4.0%。对于谐波激发案例,从两种技术获得的幅度估计之间的平均绝对百分比在较低频率(50-200Hz)下为7.4%,500Hz的29.1%。较高频率的位移估计之间的相对较大的差异被认为是跟踪标记的有限长度的结果,这被假设作为无穷大视点移动。鉴于在较低频率和脉冲长度的较低频率和脉冲壳体处看到的谐波盒的良好一致性,这种技术可能在未来对组织/传感器对ARF引起的控制,实验设置中激发的响应的研究中的洞察力。

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